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Medical Assistant Salary in Chicago, IL β€” 2026 Guide

Estimated salaries are adjusted for Chicago's cost of living (index: 114). National data from BLS OEWS 2024; city adjustments reflect local market conditions.

Medical Assistant Salary in Chicago β€” Key Numbers

$47,880
Median Salary
$40,994
25th Percentile
$56,510
75th Percentile
$65,938
90th Percentile
National median (Medical Assistant)$42,000
vs. National median+14.0%
Chicago median household income$70,100
vs. City household income-31.7%

Cost of Living in Chicago

Cost of Living Index
114(100 = avg)
Median Monthly Rent$2,288/mo
Rent-to-Income Ratio57.3%
Annual rent cost$27,456
Median Home Price$315,000
Home Price / Salary6.6Γ—
20% Down Payment$63,000
Years to save (20% rate)6.6 yrs

Rent-to-income below 28% is considered affordable; above 35% is cost-burdened. Home price multiple below 3Γ— is affordable; above 5Γ— is expensive by traditional guidelines.

Job Market in Chicago

4.6%
Unemployment Rate
9,560,000
Metro Population
31 min
Avg Commute
36.7
Median Age

Chicago has a metro population of 9,560,000, offering a large, diverse job market with many employers across all industries. The 4.6% unemployment rate is near the national average.

Medical Assistant Salary β€” Other Illinois Cities

Frequently Asked Questions

How much does a Medical Assistant make in Chicago, IL?

The estimated median salary for a Medical Assistant in Chicago is $47,880 per year (2026). This is derived from the national BLS median of $42,000 adjusted by Chicago's cost of living index (114). The typical salary range runs from $40,994 (25th percentile) to $56,510 (75th percentile), with top earners reaching $65,938.

Is Chicago affordable for a Medical Assistant?

On a $47,880 annual salary, a Medical Assistant in Chicago would spend approximately 57.3% of gross monthly income on median rent ($2,288/month). This exceeds the 35% cost-burden threshold. Many Medical Assistants in Chicago may find housing costs a significant financial pressure. The median home price of $315,000 is 6.6Γ— the annual salary.

How does a Medical Assistant's salary compare to Chicago's overall income?

Chicago's median household income is $70,100. A Medical Assistant earning the city-adjusted median of $47,880 earns 31.7% less than the typical Chicago household income. This may reflect that the profession is entry-level or that Chicago has a particularly high median household income due to high-earning industries.

Salary data from U.S. Bureau of Labor Statistics (BLS) OEWS, 2024 release. City salary estimates adjusted by cost of living index. City data from Census Bureau, BLS, Zillow, and ApartmentAdvisor (2024–2025). Last updated: March 2026.