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Medical Assistant Salary in Indianapolis, IN β€” 2026 Guide

Estimated salaries are adjusted for Indianapolis's cost of living (index: 88). National data from BLS OEWS 2024; city adjustments reflect local market conditions.

Medical Assistant Salary in Indianapolis β€” Key Numbers

$36,960
Median Salary
$31,645
25th Percentile
$43,622
75th Percentile
$50,899
90th Percentile
National median (Medical Assistant)$42,000
vs. National median-12.0%
Indianapolis median household income$64,200
vs. City household income-42.4%

Cost of Living in Indianapolis

Cost of Living Index
88(100 = avg)
Median Monthly Rent$915/mo
Rent-to-Income Ratio29.7%
Annual rent cost$10,980
Median Home Price$260,000
Home Price / Salary7.0Γ—
20% Down Payment$52,000
Years to save (20% rate)7.0 yrs

Rent-to-income below 28% is considered affordable; above 35% is cost-burdened. Home price multiple below 3Γ— is affordable; above 5Γ— is expensive by traditional guidelines.

Job Market in Indianapolis

3.7%
Unemployment Rate
2,130,000
Metro Population
24 min
Avg Commute
34.6
Median Age

Indianapolis has a metro population of 2,130,000, offering a large, diverse job market with many employers across all industries. The 3.7% unemployment rate is below the national average, suggesting a tight labor market favorable to job seekers.

Medical Assistant Salary β€” Other Indiana Cities

Frequently Asked Questions

How much does a Medical Assistant make in Indianapolis, IN?

The estimated median salary for a Medical Assistant in Indianapolis is $36,960 per year (2026). This is derived from the national BLS median of $42,000 adjusted by Indianapolis's cost of living index (88). The typical salary range runs from $31,645 (25th percentile) to $43,622 (75th percentile), with top earners reaching $50,899.

Is Indianapolis affordable for a Medical Assistant?

On a $36,960 annual salary, a Medical Assistant in Indianapolis would spend approximately 29.7% of gross monthly income on median rent ($915/month). This is approaching the 30–35% cost-burden threshold; careful budgeting is recommended. The median home price of $260,000 is 7.0Γ— the annual salary.

How does a Medical Assistant's salary compare to Indianapolis's overall income?

Indianapolis's median household income is $64,200. A Medical Assistant earning the city-adjusted median of $36,960 earns 42.4% less than the typical Indianapolis household income. This may reflect that the profession is entry-level or that Indianapolis has a particularly high median household income due to high-earning industries.

Salary data from U.S. Bureau of Labor Statistics (BLS) OEWS, 2024 release. City salary estimates adjusted by cost of living index. City data from Census Bureau, BLS, Zillow, and ApartmentAdvisor (2024–2025). Last updated: March 2026.