Medical Assistant Salary in San Francisco, CA — 2026 Guide
Estimated salaries are adjusted for San Francisco's cost of living (index: 214). National data from BLS OEWS 2024; city adjustments reflect local market conditions.
Medical Assistant Salary in San Francisco — Key Numbers
Cost of Living in San Francisco
Rent-to-income below 28% is considered affordable; above 35% is cost-burdened. Home price multiple below 3× is affordable; above 5× is expensive by traditional guidelines.
Job Market in San Francisco
San Francisco has a metro population of 4,740,000, offering a large, diverse job market with many employers across all industries. The 3.8% unemployment rate is below the national average, suggesting a tight labor market favorable to job seekers.
Financial Calculators for San Francisco
Other Professions in San Francisco
Medical Assistant Salary — Other California Cities
Frequently Asked Questions
How much does a Medical Assistant make in San Francisco, CA?
The estimated median salary for a Medical Assistant in San Francisco is $89,880 per year (2026). This is derived from the national BLS median of $42,000 adjusted by San Francisco's cost of living index (214). The typical salary range runs from $76,954 (25th percentile) to $106,080 (75th percentile), with top earners reaching $123,778.
Is San Francisco affordable for a Medical Assistant?
On a $89,880 annual salary, a Medical Assistant in San Francisco would spend approximately 46.7% of gross monthly income on median rent ($3,498/month). This exceeds the 35% cost-burden threshold. Many Medical Assistants in San Francisco may find housing costs a significant financial pressure. The median home price of $1,350,000 is 15.0× the annual salary.
How does a Medical Assistant's salary compare to San Francisco's overall income?
San Francisco's median household income is $131,000. A Medical Assistant earning the city-adjusted median of $89,880 earns 31.4% less than the typical San Francisco household income. This may reflect that the profession is entry-level or that San Francisco has a particularly high median household income due to high-earning industries.
Explore More Salary Data
Salary data from U.S. Bureau of Labor Statistics (BLS) OEWS, 2024 release. City salary estimates adjusted by cost of living index. City data from Census Bureau, BLS, Zillow, and ApartmentAdvisor (2024–2025). Last updated: March 2026.