Medical Assistant Salary in Syracuse, NY: Median $76,596 in 2026

Syracuse (NY) · COL index 86 · Unemployment 4.6% · Metro pop 660,000 · Rank #239 of 283 for Medical Assistant salary

Written by Jere Salmisto, FounderReviewed by CalcFi EditorialLast reviewed Methodology

A Medical Assistant in Syracuse earns an estimated median of $76,596 per year. That figure starts from the New York state-level BLS Occupational Employment and Wage Statistics median[1]($96,050) and scales it by Syracuse's composite cost-of-living index of 86 (US = 100). The 10th percentile comes in around $38,813; the 90th percentile reaches $137,865. After federal, New York state, and FICA taxes, a single-filer Medical Assistant takes home approximately $58,828/year — about $4,902/month or $2,263 every other week.

Compared to the national Medical Assistant median of $42,000, Syracuse pays +82.4%. Relative to the Syracuse median household income of $52,200, a Medical Assistantsalary runs +46.7%. Local unemployment is 4.6%[3], with an estimated 226 annual Medical Assistant openings inferred from metro population share and national employment (764,200).

Medical Assistant Snapshot — Syracuse (2026)

Every row cites a primary public dataset. Rent + home values use Zillow where the metro is in the ZHVI/ZORI coverage set; otherwise ACS + census tract fallbacks.

MetricSyracuseNationalSource
Medical Assistant median salary$76,596$42,000[1]
10th percentile$38,813$35,960[1]
90th percentile$137,865$57,840[1]
Annual take-home (single filer)$58,828[8][10]
Median home value (ZHVI)$254,402[5]
Median rent (ZORI)$1,619/mo[5]
HUD Fair Market Rent (2BR)$1,500/mo[6]
Median household income (ACS)$73,558[7]
Cost-of-living index86.0100.0[4]
Unemployment rate4.6%[3]

How Medical Assistant Salaries Work in Syracuse

City-level wages aren't published directly by BLS for most SOC codes. We build them by anchoring to the New York state-level OEWS median ($96,050) and scaling by Syracuse's composite cost-of-living index (86)[1][4]. That index combines Census ACS rent, Zillow ZHVI, BLS CPI, and AdvisorSmith / ApartmentAdvisor inputs to produce one number per metro. When BLS publishes a separate metro-level wage (MSA-level OEWS), that takes priority — a handful of large metros including New York, LA, Chicago, and DC have this coverage.

On top of the gross wage, the standard US payroll stack applies: federal income tax using 2025 IRS brackets and the $15,000 single standard deduction[8], FICA (Social Security 6.2% up to $176,100 wage base + Medicare 1.45%)[9], and New York state income tax at a 4.7% effective rate ($3,608/yr on the $76,596 median)[10].

Syracuse also sits inside a larger metro labor market where commute patterns, remote-work policies, and adjacent-metro wages compete. Near-national unemployment means a balanced market — employers and candidates negotiate from roughly equal positions. Median household income in the metro is $73,558, which frames what "a good Medical Assistant salary" means locally: a $$76,596 wage pays about 104% of the median household income on a single earner.

The deterministic identity: take_home = gross − federal − state − FICA − pre_tax. All math runs client-side; nothing is sent to our servers.

Cost of Living Breakdown — Syracuse

Estimated annual expense shares on a $58,828 take-home, using BLS Consumer Expenditure Survey baseline shares scaled to Syracuse's COL index of 86. Housing uses the actual median rent.

H Housing (Rent)$12,600/yr (21.4%)
F Food & Groceries$6,466/yr (11.0%)
T Transportation$5,553/yr (9.4%)
M Healthcare$3,945/yr (6.7%)
U Utilities$2,736/yr (4.7%)
S Savings & Other$27,528/yr (46.8%)

BLS Consumer Expenditure Survey shares[1], scaled by Syracuse's COL index of 86[4]. Housing uses actual median rent of $1,050/month.

Salary vs Housing Affordability in Syracuse

Renting

Monthly take-home$4,902
Affordable rent (30% rule)$1,471/mo
Median rent (ZORI)$1,619/mo
Rent-to-income ratio16.4%
VerdictVery affordable

Buying

Median home (ZHVI)$254,402
Price-to-income ratio2.3×
20% down payment$35,000
Years to down (20% savings)2.3 yr

At $4,902/mo take-home, the 30% rent rule caps housing at $1,471/mo. Syracuse's typical 1–2BR rent runs $1,619/mo[5] (HUD 2BR FMR: $1,500/mo), making rent very affordable on a median Medical Assistant salary. For homebuyers, the 2.3× price-to-income ratio is comfortable — a median {p.title} salary supports the median home in {city.name} well inside standard lender DTI caps.

How Syracuse Stacks Up for Medical Assistants

#239
Salary rank
of 283 cities
#125
Affordability
rent ÷ income
#45
Purchasing power
salary ÷ COL

Against 283 major US cities: Syracuse ranks #239 for nominal Medical Assistant salary, #125 for rent affordability, and #45 for overall purchasing power. Syracuse is mid-pack: solid nominal salaries partly absorbed by cost of living. Whether it "pays well" depends heavily on housing choices.

Nearby Cities — Medical Assistant Salary Comparison

Syracuse's closest metros, scaled by each city's cost-of-living index. Useful for relocation decisions where commute or remote-work policies allow a neighboring metro trade-off.

CityEst. salaryCOLRentvs NY
Syracuse, NY$76,59686$1,050
New York, NY$78,540187$3,600+2.5%
Buffalo, NY$36,96088$1,125-51.7%
Rochester, NY$36,12086$1,250-52.8%
Albany, NY$39,90095$1,200-47.9%
Poughkeepsie, NY$50,400120$1,700-34.2%

Sources: Census ACS[7], Zillow[5], BEA RPP[4], BLS OEWS[1].

Medical Assistant Job Market in Syracuse

~226
Est. annual openings
4.6%
Unemployment
660,000
Metro population
14%
Job growth (24–34)

Syracuse has an estimated 226 annual Medical Assistantopenings, extrapolated from the metro's share of 764,200 national Medical Assistants[1]. The 4.6% unemployment rate[3] is near the national average, with steady turnover across most sectors.

About the profession: Medical assistants support physicians and other healthcare providers with clinical and administrative tasks in offices, clinics, and hospitals. Typical entry requirement: postsecondary non-degree award. Projected growth through 2034: 14%[2].

Career Progression & Related Professions in Syracuse

Early-career Medical Assistants in Syracuse start around $38,813, reach the city median ($76,596) after 4–8 years, and hit 90th-percentile territory ($137,865) at senior / specialized levels.

Related healthcare professions in Syracuse

Calculators for Medical Assistants in Syracuse

Other professions in Syracuse

Frequently Asked Questions — Medical Assistant in Syracuse

How much does a Medical Assistant make in Syracuse, NY?

The estimated median salary for a Medical Assistant in Syracuse is $76,596/year, scaled from the BLS OEWS New York state median ($96,050) by Syracuse's composite cost-of-living index of 86 (US = 100). After federal, New York state, and FICA taxes, take-home is approximately $58,828/year or $4,902/month.

Can a Medical Assistant afford to live in Syracuse?

On $4,902/month take-home, the 30% rent rule affords $1,471/month. Syracuse's Zillow ZORI median rent is $1,619/mo, HUD's 2BR Fair Market Rent is $1,500/mo. The rent-to-income ratio works out to 16.4%, making housing very affordable for a Medical Assistant at the local median. Home-buyers face 2.3× price-to-income, needing roughly 2.3 years to save a 20% down payment at a 20% savings rate.

How much tax does a Medical Assistant pay in Syracuse?

On $76,596 gross, a Medical Assistant in Syracuse pays approximately $8,300 in federal income tax (10.8% effective), $3,608 in New York state income tax (4.7% effective), and $5,860 in FICA (Social Security + Medicare). Total effective rate: 23.2%. Some New York cities levy local income taxes in addition; check your municipal DoR before filing.

How does Syracuse rank for Medical Assistant salaries vs other cities?

Syracuse ranks #239 out of 283 tracked metros for nominal Medical Assistant salary, #125 for rent affordability (rent-to-income), and #45 for purchasing power (salary ÷ COL). The high-purchasing-power cities tend to be mid-size metros with strong local employers and moderate housing costs; the low-ranked cities trade high nominal pay for steep rents.

What is the cost-of-living breakdown for a Medical Assistant in Syracuse?

On $58,828 take-home, a reasonable baseline budget for Syracuse looks like: housing $12,600/yr (21.4%); food $6,466/yr; transportation $5,553/yr; healthcare $3,945/yr; utilities $2,736/yr; savings + discretionary $27,528/yr. Numbers use BLS Consumer Expenditure Survey shares scaled to Syracuse's COL index of 86 and the city's actual median rent.

What's the Medical Assistant job market like in Syracuse?

Syracuse's unemployment rate is 4.6% across the metro of 660,000. Estimated annual Medical Assistant openings: ~226 (extrapolated from 764,200 nationally employed and the metro's population share). The market is near national averages with steady turnover.

Do Syracuse employers pay above or below the New York median for Medical Assistants?

Yes — Syracuse's estimated Medical Assistant median of $76,596 is 82.4% above the national median. Higher nominal pay in this city partially offsets the higher cost of living; the real picture depends on housing costs and state taxes.

Methodology — How we compute this page

Wage estimate. The Syracuse median is derived from the New York state-level BLS OEWS median ($96,050), scaled by Syracuse's composite cost-of-living index of 86. When BLS publishes a direct MSA-level wage for the occupation, that takes priority over the scaled state median. Percentile bands inherit the same scale factor.

Housing + rent. Median home value uses Zillow ZHVI; median rent prefers Zillow ZORI and falls back to Census ACS median gross rent. HUD Fair Market Rents (50th-percentile 2BR) are shown where HUD publishes the metro. Price-to-income and rent-to-income ratios use the estimated Medical Assistantmedian (not the city's overall median household income) — to reflect the specific role-vs-city affordability picture.

Tax math. Federal tax uses 2025 IRS brackets and the $15,000 single standard deduction. FICA is Social Security 6.2% up to the $176,100 wage base + Medicare 1.45% (+ 0.9% Additional Medicare above $200,000). State tax uses New York's 2026 brackets from the state DoR (mirrored via Tax Foundation where the DoR's publication is paywalled or split). Local income taxes (e.g. NYC, Portland-OR supplemental, OH municipal) are NOT included — check your municipal authority for specifics.

Cost of living. The 86index is the composite used by CalcFi's /data/cities.ts, which merges Census ACS, BLS CPI shelter, Zillow ZORI, and commercial COL estimators. The COL-adjusted salary on this page assumes the statewide RPP = 107.8(BEA) approximates the state's purchasing power; cities are then scaled relative to that.

Refresh cadence. BLS OEWS releases annually (typically March); BEA RPP releases annually in December; IRS brackets adjust in October; Zillow ZHVI/ZORI updates monthly; HUD FMR publishes annually in August for the upcoming fiscal year. The dateModified shown above auto-bumps to the most recent retrievedAt on any sourced value the page consumes.

Known limits. Metro-level OEWS coverage is partial — only ~50 large MSAs have separately published occupation wages; the rest inherit state-level estimates scaled by COL. Rent and home data may trail the real-time market by 1–3 months (Zillow) or 8–12 months (ACS). Rankings are capped to the city set in our dataset (283 metros), not every incorporated US city.

Sources

Every number on this page cites a primary public dataset. Last reviewed (auto-bumped on the next ISR refresh after an ETL run).

  1. BLS Occupational Employment and Wage Statistics (OEWS) — state-level occupational wages www.bls.gov/oes. Retrieved 2026-06-08.
  2. BLS Employment Projections — 2024–34 occupational growth rates www.bls.gov/emp. Retrieved 2026-06-08.
  3. BLS Local Area Unemployment Statistics — metro-level unemployment rate www.bls.gov/lau. Retrieved 2026-06-08.
  4. Bureau of Economic Analysis — Regional Price Parities (state + metro) www.bea.gov/data/prices-inflation/regional-price-parities-state-and-metro-area. Retrieved 2026-06-08.
  5. Zillow Research — ZHVI (home value index) + ZORI (observed rent index) www.zillow.com/research/data. Retrieved 2026-06-08.
  6. HUD Fair Market Rents — 50th-percentile 2-bedroom FY www.huduser.gov/portal/datasets/fmr.html. Retrieved 2026-06-08.
  7. U.S. Census Bureau — American Community Survey (ACS) 5-year estimates, metro level www.census.gov/programs-surveys/acs. Retrieved 2026-06-08.
  8. Internal Revenue Service — Federal individual income tax brackets and standard deductions www.irs.gov/forms-pubs/about-publication-17. Retrieved 2026-06-08.
  9. Social Security Administration — OASDI / Medicare contribution and wage-base rules www.ssa.gov. Retrieved 2026-06-08.
  10. New York Department of Revenue — 2026 individual income tax brackets (accessed via Tax Foundation mirror) taxfoundation.org/data/all/state/state-income-tax-rates. Retrieved 2026-06-08.

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