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Medical Assistant Salary in Wilmington, DE β€” 2026 Guide

Estimated salaries are adjusted for Wilmington's cost of living (index: 103). National data from BLS OEWS 2024; city adjustments reflect local market conditions.

Medical Assistant Salary in Wilmington β€” Key Numbers

$43,260
Median Salary
$37,039
25th Percentile
$51,057
75th Percentile
$59,575
90th Percentile
National median (Medical Assistant)$42,000
vs. National median+3.0%
Wilmington median household income$68,800
vs. City household income-37.1%

Cost of Living in Wilmington

Cost of Living Index
103(100 = avg)
Median Monthly Rent$1,350/mo
Rent-to-Income Ratio37.4%
Annual rent cost$16,200
Median Home Price$295,000
Home Price / Salary6.8Γ—
20% Down Payment$59,000
Years to save (20% rate)6.8 yrs

Rent-to-income below 28% is considered affordable; above 35% is cost-burdened. Home price multiple below 3Γ— is affordable; above 5Γ— is expensive by traditional guidelines.

Job Market in Wilmington

4.4%
Unemployment Rate
740,000
Metro Population
25 min
Avg Commute
37.2
Median Age

Wilmington has a metro population of 740,000, offering a sizeable job market with strong opportunities across key sectors. The 4.4% unemployment rate is near the national average.

Frequently Asked Questions

How much does a Medical Assistant make in Wilmington, DE?

The estimated median salary for a Medical Assistant in Wilmington is $43,260 per year (2026). This is derived from the national BLS median of $42,000 adjusted by Wilmington's cost of living index (103). The typical salary range runs from $37,039 (25th percentile) to $51,057 (75th percentile), with top earners reaching $59,575.

Is Wilmington affordable for a Medical Assistant?

On a $43,260 annual salary, a Medical Assistant in Wilmington would spend approximately 37.4% of gross monthly income on median rent ($1,350/month). This exceeds the 35% cost-burden threshold. Many Medical Assistants in Wilmington may find housing costs a significant financial pressure. The median home price of $295,000 is 6.8Γ— the annual salary.

How does a Medical Assistant's salary compare to Wilmington's overall income?

Wilmington's median household income is $68,800. A Medical Assistant earning the city-adjusted median of $43,260 earns 37.1% less than the typical Wilmington household income. This may reflect that the profession is entry-level or that Wilmington has a particularly high median household income due to high-earning industries.

Salary data from U.S. Bureau of Labor Statistics (BLS) OEWS, 2024 release. City salary estimates adjusted by cost of living index. City data from Census Bureau, BLS, Zillow, and ApartmentAdvisor (2024–2025). Last updated: March 2026.