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Registered Nurse Salary in Denver, CO β€” 2026 Guide

Estimated salaries are adjusted for Denver's cost of living (index: 121). National data from BLS OEWS 2024; city adjustments reflect local market conditions.

Registered Nurse Salary in Denver β€” Key Numbers

$104,145
Median Salary
$83,357
25th Percentile
$130,305
75th Percentile
$160,543
90th Percentile
National median (Registered Nurse)$86,070
vs. National median+21.0%
Denver median household income$85,200
vs. City household income+22.2%

Cost of Living in Denver

Cost of Living Index
121(100 = avg)
Median Monthly Rent$1,395/mo
Rent-to-Income Ratio16.1%
Annual rent cost$16,740
Median Home Price$565,000
Home Price / Salary5.4Γ—
20% Down Payment$113,000
Years to save (20% rate)5.4 yrs

Rent-to-income below 28% is considered affordable; above 35% is cost-burdened. Home price multiple below 3Γ— is affordable; above 5Γ— is expensive by traditional guidelines.

Job Market in Denver

3.3%
Unemployment Rate
2,930,000
Metro Population
26 min
Avg Commute
36.6
Median Age

Denver has a metro population of 2,930,000, offering a large, diverse job market with many employers across all industries. The 3.3% unemployment rate is below the national average, suggesting a tight labor market favorable to job seekers.

Registered Nurse Salary β€” Other Colorado Cities

Frequently Asked Questions

How much does a Registered Nurse make in Denver, CO?

The estimated median salary for a Registered Nurse in Denver is $104,145 per year (2026). This is derived from the national BLS median of $86,070 adjusted by Denver's cost of living index (121). The typical salary range runs from $83,357 (25th percentile) to $130,305 (75th percentile), with top earners reaching $160,543.

Is Denver affordable for a Registered Nurse?

On a $104,145 annual salary, a Registered Nurse in Denver would spend approximately 16.1% of gross monthly income on median rent ($1,395/month). This is well within the 28% affordability threshold, making Denver relatively affordable for this profession. The median home price of $565,000 is 5.4Γ— the annual salary.

How does a Registered Nurse's salary compare to Denver's overall income?

Denver's median household income is $85,200. A Registered Nurse earning the city-adjusted median of $104,145 earns 22.2% more than the typical Denver household β€” placing them solidly in the middle-to-upper income tier for the city.

Salary data from U.S. Bureau of Labor Statistics (BLS) OEWS, 2024 release. City salary estimates adjusted by cost of living index. City data from Census Bureau, BLS, Zillow, and ApartmentAdvisor (2024–2025). Last updated: March 2026.