Pharmacist Salary in South Dakota: Median $66,860 in 2026

South Dakota (SD) · No state income tax · RPP 88.1 · Rank #5 of 51 for take-home

Written by Jere Salmisto, FounderReviewed by CalcFi EditorialLast reviewed Methodology

A Pharmacist in South Dakota earns a median of $66,860 per year, based on the most recent 2023 BLS Occupational Employment and Wage Statistics release[1]adjusted for South Dakota's Bureau of Economic Analysis Regional Price Parity of 88.1 (US = 100)[2]. The 10th percentile starts at about $41,440, while the 90th percentile reaches $133,080. After federal income tax, FICA, and no South Dakota income tax (one of the handful of no-tax states), a single-filer takes home roughly $55,588/year — about $4,632/month or $2,138 every other week.

Because South Dakota is a low-cost state (RPP 88.1), the real purchasing power of that take-home is roughly $63,061 in national-average terms. Among all 51 jurisdictions in the US, South Dakota ranks #5 for take-home pay on a $66,860 gross — a Pharmacist keeps 83.1% of every dollar earned after federal, state, and payroll taxes. Nationally, BLS projects -3% growth in this occupation through 2034[3], which typically translates into comparable demand at the South Dakota state level.

Pharmacist Salary Snapshot — South Dakota (2026)

Every row cites a primary public dataset. Percentiles are BLS OEWS state-level where published; otherwise scaled from the national distribution by South Dakota's RPP.

MetricSouth DakotaNational
Median wage $66,860$136,030
10th percentile $41,440$117,540 (P25)
90th percentile$133,080$181,730
State employment 34,830311,560
Cost-of-living index 88.1100.0
Annual take-home $55,588$103,910*
Take-home rank #5
COL-adjusted take-home $63,061

*National reference column uses Texas as a no-income-tax baseline to isolate the state-tax effect.

How Pharmacist Salaries Work in South Dakota

A Pharmacist paycheck in South Dakota is stacked the same way as every US paycheck: gross wage, then federal income tax withholding based on IRS Publication 17 bracket tables[4], then FICA — Social Security 6.2% (up to the 2025 wage base of $176,100) and Medicare 1.45% (plus 0.9% above $200,000)[5], then whatever the state layers on top. South Dakota is one of a small group of states with no individual income tax. On a $66,860 gross, you save roughly $3,009–$4,680 per year vs an average-tax state — that's the South Dakota "tax premium" built into take-home.[6]

Beyond income tax, two South Dakota floors matter. State minimum wage sets the price of entry-level labor and pulls up the bottom of the wage distribution[7]. Cost of living — measured by the BEA Regional Price Parity of 88.1 — sets the price of housing, groceries, utilities, and services that determine how far the paycheck goes[2]. Together these two numbers explain most of the variance between nominal and real Pharmacist compensation across states.

Local demand also matters. State-level OEWS puts about 34,830 people in this SOC group across South Dakota, which lets employers compete on wages rather than benefits alone.The lower cost base in this state means employers can offer 5–10% below the national nominal median and still win talent competition against mid-cost states. Two workers with identical Pharmacist titles can therefore see very different take-home outcomes depending purely on South Dakota's tax and cost profile.

The complete identity: take_home = gross − federal_tax − state_tax − FICA − pre_tax_deductions. Every number in the table above, and every paycheck calculator on CalcFi, runs that identity client-side. No inputs leave your browser.

Pharmacist Salary by City in South Dakota

Estimated median Pharmacistsalary by metro, using each city's composite cost-of-living index against the South Dakota statewide OEWS median. Rent is ACS + Zillow ZORI; unemployment is BLS LAUS.

CityEst. median salaryMedian rentEst. net (monthly)
Sioux Falls, SD$60,843$865/mo$4,251
Rapid City, SD$62,180$1,050/mo$4,341

Sources: Zillow ZORI / Census ACS[9], BLS OEWS[1], BEA RPP[2]. City-level salary estimates scale the statewide OEWS median by each metro's composite COL index; actual employer wages can deviate by ±10–20% depending on industry mix.

South Dakota vs Neighbor States — Pharmacist Take-Home

Same $66,860 gross salary, different state tax regimes. The table shows what a single-filer Pharmacistwould net in each bordering state. Useful if you're comparing job offers across state lines or considering a relocation.

StateState tax (eff.)Annual take-home
South DakotaNone$55,588
Iowa3.8%$53,047
Minnesota4.0%$52,884
Montana4.2%$52,781
Nebraska3.8%$53,036

★ = no state individual income tax. Numbers assume identical $$66,860 gross, single filer, standard deduction. Real-world comparisons should also factor in cost-of-living differences (RPP) and any local income taxes[6][2].

Cost of Living vs Salary — Purchasing Power in South Dakota

Nominal dollars only tell part of the story. The BEA Regional Price Parity for South Dakota is 88.1 (US = 100)[2]. That means an identical basket of goods and services costs 11.9% less in South Dakota than in an average-cost US location. A Pharmacist's $55,588 nominal take-home therefore equals about $63,061 of national-average purchasing power.

Concretely, that shows up in three budget buckets:

  • Housing. The single biggest driver. In lower-RPP states like South Dakota, housing often stays under 25% of take-home for a median-salary Pharmacist.
  • Groceries + services.BEA publishes sub-indexes for goods, rents, and other services. Goods tend to be closer to national averages (they're traded); services and rents are where the big state-level spreads show up.
  • State + local tax. South Dakota's lack of state income tax improves real purchasing power by 6.5% to 9.0% vs average-tax states on a $66,860 salary — a meaningful wedge that stacks on top of the RPP effect.

The classic rule of thumb — "aim for take-home ≥ 3x your monthly housing cost" — holds in South Dakota only above the 60th-percentile wage band for this occupation. Below that threshold, the RPP hit compounds with fixed housing costs and the real savings rate collapses. Above it, South Dakota's lower cost base makes this a strong wealth-building state for Pharmacists.

Where Pharmacists Work in South Dakota

BLS OEWS attributes roughly 34,830 South Dakota workers to the Healthcare major group containing Pharmacist.Major hiring industries for Pharmacists tend to cluster into three groups: (1) large private employers in healthcare (primary source of wage pressure at the top of the distribution); (2) state and local government — consistently one of the top five healthcare employers in most US states; and (3) federal government and contractors — especially relevant in states with large DoD or federal civilian footprints.

Typical entry requirement for this role is a doctoral degree (pharmd). Common tax-deductible professional expenses that Pharmacists in South Dakota can consider — where itemizing makes sense — include: State pharmacist license fees, Continuing pharmacy education, Professional association dues (APhA), Student loan interest (pharmacy school). Confirm deductibility with a CPA; 2017 TCJA changes limited unreimbursed employee expenses, but self-employed or contractor Pharmacists still get full Schedule C treatment.

Career Progression & Related Professions in South Dakota

Early-career Pharmacists in South Dakota typically start near the 10th percentile ($41,440), reach the median ($66,860) after 4–8 years, and enter the 90th percentile ($133,080) with senior or specialized roles. Related healthcare occupations in South Dakota:

Useful calculators for Pharmacists in South Dakota

Other professions in South Dakota

Local context: South Dakota

Housing economics in South Dakota. The median home value runs 17.6% below the U.S. baseline for South Dakota is $295,000 per Zillow's home-value index. Effective property tax sits at 0.82% of assessed value, below the 0.99% national average tracked by the Tax Foundation. Lenders in South Dakota have quoted 6.30% on the 30-year fixed product over the trailing four-week window per Freddie Mac PMMS — the prevailing posted rate before any borrower-specific lock-ins.

Income and tax climate. Median household income in South Dakota reaches $79,850 per the ACS five-year vintage, pulling above the $78,538 U.S. median. South Dakota's top marginal state income tax bracket lands at 0.00% — one of nine states that levies no broad-based income tax, shifting the revenue burden onto sales, property, and severance levies. BEA's Regional Price Parity scores South Dakota at 89.0 (national = 100), meaning a dollar in South Dakota buys 112¢ — more goods and services than the same dollar nationally.

How South Dakota affects take-home pay. Federal FICA, Medicare, and income tax are identical for every wage earner regardless of state. South Dakota's contribution is the state income tax overlay plus any state-level disability or paid-family-leave deductions. Where applicable, the calculator factors in the local minimum wage when an hourly-to-salary conversion is involved, and uses BLS OEWS median earnings for South Dakota as the contextual baseline shown alongside your inputs.

Local context as of 2026-06-13. Live data sources are listed in the Sources section below; each metric carries its own retrieval date.

South Dakota versus the U.S. baseline

How does South Dakota stack up against the national average on the metrics that drive the calculators on this page? The table below pairs the South Dakota-specific reading against the U.S. baseline so you can see at a glance whether your local scenario runs above or below typical. Three to five percentage points of difference on most of these inputs translates into meaningful changes in calculator output — for example, a 50-basis-point difference in mortgage rate moves the monthly payment on a $400,000 30-year loan by roughly $130.

MetricSouth DakotaU.S. baselineDifference
Median Pharmacist salary[bls-oews]$66,860$136,030-50.8%
Annual take-home (single filer)[irs]$55,588$103,910-46.5%
Top marginal state income tax[state-dor]None~4.08% (volume-weighted)−4.08 pp
Cost-of-living index (BEA RPP)[bea-rpp]88.1100.0-11.9 pts
Effective combined tax rate[irs]16.9%~24-28% (typical)

How to use the Pharmacist salary calculator for South Dakota

Walk through estimating Pharmacist pay in South Dakota using state-specific BLS OEWS percentiles, IRS / state tax math, and BEA cost-of-living adjustments.

  1. Pre-fill with local dataEach calculator on this page loads with state- or city-specific defaults pulled live from primary sources (FRED, BLS, Zillow, Freddie Mac PMMS, IRS, BEA). The blue values shown next to each input are the local averages so you can see how your scenario compares to the typical case before changing anything.
  2. Override the inputs you controlChange any field to model your actual situation. The math reruns in your browser the moment you change a value — no signup, no API call, no data transmission. Hover over the small (i) icon next to each label to see the formula that field feeds and where the default came from.
  3. Read the derived valuesThe result panel shows the primary calculation (monthly payment, take-home pay, savings projection, etc.) plus the intermediate values that drive it. Each line item is labeled with the formula component it represents so you can verify the arithmetic against any agency publication, textbook, or competing calculator.
  4. Adjust assumptions and re-runMost calculators have a section for assumption inputs that are easy to overlook — annual raises, expected return, inflation, vacancy rate, depreciation schedule, marginal vs. effective tax treatment. The defaults are conservative; aggressive scenarios usually require explicit overrides.
  5. Save to "My Numbers"When the inputs match your reality, click Save to "My Numbers". The values persist to your device's local storage (IndexedDB) and reload automatically on your next visit. Nothing is transmitted to any CalcFi server — the saved-state feature is deliberately client-side only for privacy.
  6. Compare scenarios side by sideMost calculators offer a comparison view that shows two or more scenarios side by side. Use this to model decision points: 15-year vs 30-year mortgage, Roth vs Traditional IRA, salary vs hourly, lease vs buy. The comparison view also produces a shareable summary you can download as PNG or PDF.

Frequently Asked Questions — Pharmacist in South Dakota

What is the median salary for a Pharmacist in South Dakota?

Based on BLS OEWS 2023 state-level data and BEA RPP cost-of-living adjustments, the median Pharmacist in South Dakota earns approximately $66,860/year. The 10th percentile is around $41,440 and the 90th percentile reaches $133,080. State OEWS lists about 34,830 people employed in this occupational group statewide.

How much does a Pharmacist take home after taxes in South Dakota?

On a $66,860 gross salary, a single-filer Pharmacist in South Dakota takes home approximately $55,588/year ($4,632/month, $2,138 bi-weekly) after federal income tax (9.2%), FICA (Social Security + Medicare). Combined effective rate: 16.9%. Numbers assume the standard deduction; itemizing or pre-tax 401(k) contributions will raise your net.

How does South Dakota compare to other states for Pharmacist take-home pay?

South Dakota ranks #5 out of 51 for Pharmacist take-home pay at the $66,860 state median salary. The best state for this gross is Alaska ($55,588/yr take-home) and the worst is Oregon ($50,292/yr). A Pharmacist in South Dakota keeps 83.1% of every gross dollar earned.

What is the cost-of-living-adjusted salary for a Pharmacist in South Dakota?

South Dakota's BEA regional price parity is 88.1 (US = 100), meaning the state's $55,588 take-home is equivalent to about $63,061 of national-average purchasing power. Because living costs are 11.9% below average, your salary stretches further in South Dakota than in an average-cost state.

How do Pharmacist salaries vary by city in South Dakota?

Within South Dakota, Pharmacist salaries scale with metro-level cost of living. For example, Sioux Falls (91 COL index, estimated median $60,843), Rapid City (93 COL index, estimated median $62,180). Higher-COL metros pay more in nominal terms, but after rent and groceries the net purchasing power often evens out.

What state taxes affect a Pharmacist paycheck in South Dakota?

South Dakota has no state individual income tax. A Pharmacist earning $66,860 saves roughly $3,009–$4,680 annually compared to an average-tax state. You still pay federal income tax and FICA. South Dakota's property tax rate is 1.3% and state sales tax is 4.5%. No state income tax.

What is the career outlook for Pharmacists in South Dakota?

Nationally, BLS Employment Projections expect -3% growth in the Pharmacist occupation through 2034. South Dakota-specific demand typically tracks national trends, with adjustments for local industry mix. The typical entry requirement is a doctoral degree (pharmd), and Pharmacists dispense prescription medications and provide expertise on their safe use. They work in retail pharmacies, hospitals, and clinical settings.

Methodology — How we compute this page

Wage percentiles. Primary source is the BLS Occupational Employment and Wage Statistics (OEWS) state-level release, 2023 vintage. We pull the state row for the SOC major group that contains Pharmacist (29-0000). When the BLS suppresses a cell for data-quality reasons, we fall back to the national percentile scaled by South Dakota's BEA RPP — the same method BLS's own reports use.

Take-home tax math. Federal tax uses 2025 IRS brackets and the single standard deduction ($15,000). State tax uses the South Dakota2026 brackets from the state Department of Revenue, mirrored by Tax Foundation where the DoR's PDF is paywalled or split across multiple publications. FICA is Social Security 6.2% (capped at $176,100 wage base) + Medicare 1.45% + 0.9% Additional Medicare above $200,000. All math is the deterministic identity take_home = gross − federal − state − FICA; no Monte Carlo or estimator models.

Cost-of-living adjustments.We use BEA's Regional Price Parities (RPP) for all-items. RPP is a purchasing-power index where US = 100. Real (COL-adjusted) take-home is nominal_take_home / (RPP / 100). City-level estimates scale the statewide OEWS median by each metro's composite COL index from our /data/cities.ts dataset, which merges Census ACS, BLS, and Zillow inputs.

Refresh cadence. BLS OEWS releases once a year (typically March, for the prior May reference period). BEA RPP releases once a year in December. Federal tax brackets are updated annually by the IRS (October inflation adjustment). State brackets refresh per legislative calendar. The dateModified shown above auto-bumps when any sourced value's retrievedAt changes — no template edit required.

Known limits.Statewide medians mask large intra-state variance — metros and rural counties can differ by 20–40% for the same SOC code. We don't currently bake in local income taxes (e.g. NYC, Portland-OR supplemental). We assume single-filer, standard deduction, no pre-tax contributions; users with itemized deductions or 401(k) deferrals should plug their specifics into the linked calculators. Suppressed BLS cells fall through to national-scaled fallbacks, which can under-estimate demand in specialty states.

Sources

Every number on this page cites a primary public dataset. Last reviewed (auto-bumped on the next ISR refresh after an ETL run).

  1. BLS Occupational Employment and Wage Statistics (OEWS) — state-level occupational wages www.bls.gov/oes. Retrieved 2026-06-13.
  2. BLS Employment Projections — 2024–34 occupational growth rates www.bls.gov/emp. Retrieved 2026-06-13.
  3. Bureau of Economic Analysis — Regional Price Parities by State (all-items RPP) www.bea.gov/data/prices-inflation/regional-price-parities-state-and-metro-area. Retrieved 2026-06-13.
  4. Internal Revenue Service — Federal individual income tax brackets and standard deductions www.irs.gov/forms-pubs/about-publication-17. Retrieved 2026-06-13.
  5. Social Security Administration — OASDI / Medicare contribution and wage-base rules www.ssa.gov. Retrieved 2026-06-13.
  6. South Dakota Department of Revenue — 2026 individual income tax brackets (accessed via Tax Foundation mirror) taxfoundation.org/data/all/state/state-income-tax-rates. Retrieved 2026-06-13.
  7. U.S. Department of Labor, Wage and Hour Division — State Minimum Wage Laws www.dol.gov/agencies/whd/minimum-wage/state. Retrieved 2026-06-13.
  8. FRED (Federal Reserve Economic Data) — real median household income per state fred.stlouisfed.org. Retrieved 2026-06-13.
  9. U.S. Census Bureau — American Community Survey (ACS) 5-year estimates www.census.gov/programs-surveys/acs. Retrieved 2026-06-13.

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For personalized calculations, use the South Dakota Paycheck Calculator.