How does a Registered Nurse's salary in San Antonio compare to the rest of Texas?

San Antonio's cost of living index is 92 vs. the national average of 100, so salaries are adjusted downward accordingly. A Registered Nurse earning the city-adjusted median of $79,184 earns $20,584 more than the median household income in San Antonio ($58,600).

Registered Nurse Salary in San Antonio, TX — 2026 Guide

Estimated salaries are adjusted for San Antonio's cost of living (index: 92). National data from BLS OEWS 2024; city adjustments reflect local market conditions.

Registered Nurse Salary in San Antonio — Key Numbers

$79,184

Median Salary

$63,379

25th Percentile

$99,075

75th Percentile

$122,066

90th Percentile

National median (Registered Nurse)$86,070

vs. National median-8.0%

San Antonio median household income$58,600

vs. City household income+35.1%

Cost of Living in San Antonio

Cost of Living Index

92(100 = avg)

Median Monthly Rent$899/mo

Rent-to-Income Ratio13.6%

Annual rent cost$10,788

Median Home Price$270,000

Home Price / Salary3.4×

20% Down Payment$54,000

Years to save (20% rate)3.4 yrs

Rent-to-income below 28% is considered affordable; above 35% is cost-burdened. Home price multiple below 3× is affordable; above 5× is expensive by traditional guidelines.

Job Market in San Antonio

3.8%

Unemployment Rate

2,650,000

Metro Population

26 min

Avg Commute

34.3

Median Age

San Antonio has a metro population of 2,650,000, offering a large, diverse job market with many employers across all industries. The 3.8% unemployment rate is below the national average, suggesting a tight labor market favorable to job seekers.

Financial Calculators for San Antonio

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Cost of Living — San Antonio

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Registered Nurse Salary in Texas

Statewide salary breakdown

Other Professions in San Antonio

Physician$210,956 Chief Executive Officer$193,200 Dentist$161,469 IT Manager$155,949 Marketing Manager$145,010 Lawyer$134,099

Registered Nurse Salary — Other Texas Cities

Houston, TX$86,931 Dallas, TX$90,374 Austin, TX$104,145 Fort Worth, TX$85,209 El Paso, TX$72,299

Frequently Asked Questions

How much does a Registered Nurse make in San Antonio, TX?

The estimated median salary for a Registered Nurse in San Antonio is $79,184 per year (2026). This is derived from the national BLS median of $86,070 adjusted by San Antonio's cost of living index (92). The typical salary range runs from $63,379 (25th percentile) to $99,075 (75th percentile), with top earners reaching $122,066.

Is San Antonio affordable for a Registered Nurse?

On a $79,184 annual salary, a Registered Nurse in San Antonio would spend approximately 13.6% of gross monthly income on median rent ($899/month). This is well within the 28% affordability threshold, making San Antonio relatively affordable for this profession. The median home price of $270,000 is 3.4× the annual salary.

How does a Registered Nurse's salary compare to San Antonio's overall income?

San Antonio's median household income is $58,600. A Registered Nurse earning the city-adjusted median of $79,184 earns 35.1% more than the typical San Antonio household — placing them solidly in the middle-to-upper income tier for the city.

Explore More Salary Data

Registered Nurse — National Registered Nurse in Texas All Salary Guides

Salary data from U.S. Bureau of Labor Statistics (BLS) OEWS, 2024 release. City salary estimates adjusted by cost of living index. City data from Census Bureau, BLS, Zillow, and ApartmentAdvisor (2024–2025). Last updated: March 2026.